Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867916 | 0.93 | KMT2A (0.51) | ALDH1A1KMT2ATDP1HPGDCDC25B | |
| SCHEMBL10522472 | 0.86 | KMT2A (0.41) | ALDH1A1RECQLMMP8KMT2ATDP1 | |
| SCHEMBL4419400 | 0.84 | ALDH1A1 (0.62) | ALDH1A1RECQLMMP8PTPRCPTPN1 | |
| SCHEMBL10709206 | 0.84 | POLB (0.50) | ALDH1A1KMT2ATDP1HPGDCDC25B | |
| SCHEMBL8871911 | 0.83 | TDP1 (0.54) | MMP8KMT2ATDP1KDM4EMEN1 | |
| SCHEMBL10422488 | 0.82 | KMT2A (0.44) | ALDH1A1KMT2ATDP1HPGDCDC25B | |
| SCHEMBL10390172 | 0.82 | KMT2A (0.44) | ALDH1A1KMT2ATDP1HPGDCDC25B | |
| SCHEMBL10522745 | 0.81 | KMT2A (0.44) | ALDH1A1MMP8KMT2ATDP1HPGD | |
| SCHEMBL10522741 | 0.81 | KMT2A (0.44) | ALDH1A1MMP8KMT2ATDP1HPGD | |
| SCHEMBL29277098 | 0.81 | KMT2A (0.50) | ALDH1A1KMT2ATDP1HPGDCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |