Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868045 | 0.93 | ALDH1A1 (0.48) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL10390172 | 0.88 | KMT2A (0.44) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL10422488 | 0.88 | KMT2A (0.44) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL10709206 | 0.87 | POLB (0.50) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL29277098 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL10391193 | 0.86 | KMT2A (0.56) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL9848642 | 0.84 | ATM (0.52) | KMT2AALDH1A1TDP1KDM4EATM | |
| SCHEMBL10522745 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1HPGDCDC25BTDP1 | |
| SCHEMBL10522472 | 0.84 | KMT2A (0.41) | KMT2AALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL10522741 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1HPGDCDC25BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |