Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447574 | 0.87 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL10787062 | 0.83 | MEN1 (0.37) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL4809603 | 0.80 | ALOX5 (0.42) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL4809821 | 0.80 | ALOX5 (0.42) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL20272491 | 0.80 | MEN1 (0.33) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL5469107 | 0.79 | TSHR (0.33) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25233759 | 0.78 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL5468938 | 0.77 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL31033440 | 0.75 | MEN1 (0.35) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL9908423 | 0.75 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177696-A1 | Macrolide alkylation process | ABBOTT LABORATORIES (US) | 1986-04-16 | — | — | EP | disclosed |