Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24895106 | 0.81 | HPGD (0.63) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL9558286 | 0.81 | NR4A1 (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL3197711 | 0.80 | ALDH1A1 (0.61) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL10527760 | 0.80 | CDC25B (0.55) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL10012443 | 0.80 | NR4A1 (0.67) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL11857852 | 0.80 | NR4A1 (0.67) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL27985 | 0.79 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL29406795 | 0.79 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6917090 | 0.79 | ALDH1A1 (0.59) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6917086 | 0.79 | ALDH1A1 (0.59) | NR4A1NR4A2NR4A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182499-A1 | N-(6-methoxy-5-(perfluoroalkyl)-1-naphtolyl)-N-metylglycines and their thionaphthoyl analogs | AYERST, MCKENNA AND HARRISON INC. (CA) | 1986-05-28 | — | — | EP | claimed |