Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909534 | 0.88 | ALDH1A1 (0.41) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL23909595 | 0.88 | KMT2A (0.42) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL1048314 | 0.85 | CYP1A2 (0.52) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL10015553 | 0.84 | LDHA (0.47) | ALDH1A1CYP3A4CYP2C9TDP1L3MBTL1 | |
| SCHEMBL29996206 | 0.82 | NR4A1 (0.55) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL31401786 | 0.82 | NR4A1 (0.55) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL464977 | 0.82 | NR4A1 (0.55) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL10869342 | 0.81 | NR4A1 (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL24895106 | 0.81 | HPGD (0.63) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL3197711 | 0.80 | ALDH1A1 (0.61) | NR4A1NR4A2NR4A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332425-B1 | PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5075406-A | Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5011936-A | Using composite salt consisting of at least two of silica, magnesia and alumina | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0332425-A1 | Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-13 | — | — | EP | disclosed |