Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873486 | 0.92 | CASP1 (0.53) | CASP1HSD17B10MTORPOLBALDH1A1 | |
| SCHEMBL10869613 | 0.92 | CASP1 (0.53) | CASP1HSD17B10MTORPOLBALDH1A1 | |
| SCHEMBL10870398 | 0.88 | MTOR (0.45) | CASP1HSD17B10MTORPOLBALDH1A1 | |
| SCHEMBL10707421 | 0.82 | PDE4A (0.65) | MTORPOLBALDH1A1PDE4APDE4B | |
| SCHEMBL10705682 | 0.82 | PDE4A (0.65) | MTORPOLBALDH1A1PDE4APDE4B | |
| SCHEMBL10870587 | 0.81 | PDE4A (0.60) | CASP1HSD17B10ALDH1A1LMNAPDE4A | |
| SCHEMBL10869809 | 0.79 | PDE4A (0.49) | CASP1HSD17B10POLBALDH1A1LMNA | |
| SCHEMBL10870626 | 0.78 | PDE4A (0.41) | CASP1HSD17B10ALDH1A1LMNAPDE4A | |
| SCHEMBL10870316 | 0.77 | PDE4A (0.65) | POLBALDH1A1LMNAPDE4APDE4B | |
| SCHEMBL10704532 | 0.76 | PDE4A (0.42) | MTORPOLBALDH1A1LMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185259-A2 | Pteridines, process for their preparation, and their use as intermediates or as medicaments | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |