Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334629 | 0.91 | HDAC8 (0.47) | ALDH1A1TDP2NSD2PAX8ABL1 | |
| SCHEMBL6332459 | 0.78 | HDAC8 (0.50) | ALDH1A1TDP2NSD2PAX8ABL1 | |
| SCHEMBL2493946 | 0.78 | DNMT1 (0.62) | MEN1KMT2ADNMT1RAD52UHRF1 | |
| SCHEMBL31038690 | 0.75 | CDK5 (0.39) | DNMT1RAD52UHRF1 | |
| SCHEMBL9868719 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TDP2NSD2PAX8ABL1 | |
| SCHEMBL10822451 | 0.73 | ADORA3 (0.44) | DNMT1RAD52UHRF1 | |
| SCHEMBL10822464 | 0.72 | DNMT1 (0.44) | ALDH1A1GAADNMT1RAD52UHRF1 | |
| SCHEMBL9038126 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP2NSD2PAX8ABL1 | |
| SCHEMBL11800087 | 0.70 | TSHR (0.41) | ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5322696 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183993-A2 | 2H-imidazo[1',2':1,2]pyrrolo[3,4-b]pyridines and their use as anti-weed agent | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-06-11 | — | — | EP | claimed |