Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247174 | 0.97 | TDP1 (0.56) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10868377 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10869069 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10869207 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10868646 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10868720 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL8719254 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL10868865 | 0.96 | TSHR (0.54) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL1249527 | 0.91 | THRB (0.58) | TDP1THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL434675 | 0.88 | TDP1 (0.68) | TDP1THRBTSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184482-A1 | Thermotropical polymers with chiral lateral chains, and process for their preparation | THOMSON-CSF (FR) | 1986-06-11 | — | — | EP | disclosed |