Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177506 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| Lithium SCHEMBL7177510 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| SCHEMBL7189939 | 0.94 | TYK2 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| Lithium SCHEMBL7189944 | 0.94 | TYK2 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| Lithium SCHEMBL7187695 | 0.89 | MEN1 (0.40) | ALDH1A1GAAMAPTRAB9ALMNA | |
| SCHEMBL7187687 | 0.89 | MEN1 (0.40) | ALDH1A1GAAMAPTRAB9ALMNA | |
| Lithium SCHEMBL7185641 | 0.86 | ALDH1A1 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| SCHEMBL7185635 | 0.86 | ALDH1A1 (0.39) | ALDH1A1GAAPOLBMAPTPTGS2 | |
| SCHEMBL7180684 | 0.85 | S1PR4 (0.38) | ALDH1A1GAAMEN1KMT2ACYP1A2 | |
| Lithium SCHEMBL7180693 | 0.85 | S1PR4 (0.38) | ALDH1A1GAAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184095-A2 | Bisacylphosphinoxides, their preparation and use | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1986-06-11 | — | — | EP | disclosed |