SCHEMBL10870263

SCHEMBL10870263

CC[C@](C)(CC=O)OCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
RIPK1 Q13546 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
IDO1 P14902 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35
CDK4 P11802 1/20 0.35
CCNB1 P14635 1/20 0.35
CCND1 P24385 1/20 0.35
CCNB3 Q8WWL7 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13931102 0.85 TSHR (0.46) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL11985625 0.82 TSHR (0.40) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL22775989 0.82 TSHR (0.40) ALDH1A1TSHRKDM4ESMN1; SMN2IDO1
SCHEMBL19185379 0.79 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL4572017 0.79 TSHR (0.40) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL13463337 0.78 TSHR (0.41) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL16177925 0.78 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL10838991 0.77 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL10838389 0.77 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL10838383 0.77 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61087636-A None JP disclosed
JP-S6187636-A ALPHA-SUBSTITUTED ALDEHYDE SUMITOMO CHEM CO LTD 1986-05-06 JP disclosed