Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931102 | 0.88 | TSHR (0.46) | TSHRIDO1TP53AGXTMAPT | |
| SCHEMBL11985625 | 0.81 | TSHR (0.40) | TSHRIDO1TP53AGXTMAPT | |
| SCHEMBL19185379 | 0.79 | ALDH1A1 (0.38) | TSHRIDO1MAPTKDM4EMEN1 | |
| SCHEMBL10870263 | 0.79 | ALDH1A1 (0.38) | TSHRIDO1MAPTKDM4EMEN1 | |
| SCHEMBL13463337 | 0.77 | TSHR (0.41) | TSHRIDO1TP53MAPTKDM4E | |
| SCHEMBL14000911 | 0.77 | TSHR (0.43) | TSHRIDO1TP53AGXTMAPT | |
| SCHEMBL12879586 | 0.76 | TSHR (0.46) | TSHRIDO1TP53AGXTMAPT | |
| SCHEMBL21706155 | 0.76 | TSHR (0.39) | TSHRIDO1AGXTMAPTKDM4E | |
| SCHEMBL29054323 | 0.75 | TSHR (0.44) | TSHRIDO1TP53AGXTMAPT | |
| SCHEMBL6230320 | 0.75 | TSHR (0.44) | TSHRIDO1TP53AGXTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122136-A1 | Self-immolative probes for enzyme activity detection | ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122136-A1 | Self-immolative probes for enzyme activity detection | SORD, SI, IMMT | TSHR 2887/4885IDO1 151/4885TP53 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.