Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687991 | 0.92 | L3MBTL1 (0.66) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL11670896 | 0.87 | TDP1 (0.55) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL10871639 | 0.85 | ATM (0.53) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL867886 | 0.83 | L3MBTL1 (1.00) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL11076613 | 0.81 | L3MBTL1 (0.53) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL874534 | 0.81 | L3MBTL1 (0.68) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL11177136 | 0.79 | L3MBTL1 (0.66) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL3276088 | 0.79 | RAB9A (0.75) | L3MBTL1TDP1ATMNPSR1RAB9A | |
| SCHEMBL15518998 | 0.79 | L3MBTL1 (0.66) | L3MBTL1TDP1ATMNPSR1PTGES | |
| SCHEMBL6763307 | 0.79 | L3MBTL1 (0.71) | L3MBTL1TDP1ATMNPSR1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192150-A2 | 1-Acyl-1-phenyl ureas | BAYER AG (DE) | 1986-08-27 | — | — | EP | disclosed |