Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868299 | 0.88 | SLC1A3 (0.45) | TDP1SLC1A3SLC1A2SLC1A1CTNNB1 | |
| SCHEMBL10870476 | 0.81 | TDP1 (0.47) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8083878 | 0.74 | SLC1A3 (0.52) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL9226500 | 0.74 | SLC1A3 (0.48) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL25034482 | 0.73 | ATM (0.57) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL7325136 | 0.73 | KMT2A (0.49) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| Acetic Acid SCHEMBL8578209 | 0.72 | TDP1 (0.56) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL2575317 | 0.71 | TDP1 (0.59) | TDP1KDM4ESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23645082 | 0.71 | SLC1A3 (0.56) | TDP1KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL10870041 | 0.71 | TDP1 (0.44) | TDP1KDM4EALDH1A1ATMCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |