Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868446 | 0.86 | HRH4 (0.49) | TDP1CTNNB1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10522072 | 0.85 | HRH4 (0.50) | TDP1CTNNB1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10871839 | 0.81 | TDP1 (0.46) | TDP1KDM4EALDH1A1CTNNB1L3MBTL1 | |
| SCHEMBL6677809 | 0.79 | CTNNB1 (0.63) | TDP1CTNNB1HRH4SLC1A3SLC1A2 | |
| SCHEMBL9556717 | 0.77 | CTNNB1 (0.48) | TDP1CTNNB1HRH4L3MBTL1SLC1A3 | |
| SCHEMBL7353938 | 0.77 | CTNNB1 (0.48) | TDP1CTNNB1HRH4L3MBTL1SLC1A3 | |
| SCHEMBL3814684 | 0.77 | CTNNB1 (0.56) | TDP1CTNNB1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10477661 | 0.76 | CTNNB1 (0.50) | TDP1KDM4EALDH1A1CTNNB1HRH4 | |
| SCHEMBL10389712 | 0.76 | CTNNB1 (0.50) | TDP1CTNNB1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7280245 | 0.76 | CTNNB1 (0.52) | TDP1CTNNB1HRH4SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |