Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989057 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1HPGDKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7666645 | 0.76 | TDP1 (0.33) | ALDH1A1HPGDKMT2ALMNASMN1; SMN2 | |
| SCHEMBL11257239 | 0.76 | CES1 (0.33) | ALDH1A1HPGDKMT2ASMN1; SMN2TSHR | |
| SCHEMBL2332592 | 0.76 | HPGD (0.46) | ALDH1A1HPGDLMNASMN1; SMN2TSHR | |
| SCHEMBL1714625 | 0.76 | PAM (0.32) | HPGDKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL8382976 | 0.75 | KDM4E (0.36) | ALDH1A1HPGDSMN1; SMN2GAATSHR | |
| SCHEMBL7516064 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL689065 | 0.75 | FFAR1 (0.36) | FFAR1ALDH1A1KMT2AMIFGAA | |
| SCHEMBL696680 | 0.75 | GSK3B (0.48) | HPGDKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL6952030 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HPGDKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070863-C | Phosphonic diester derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1206419-A | Phosphonic acid diester derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-01-27 | — | — | CN | disclosed |
| EP-0192167-A1 | Use of thio-substitued ketones as photoinitiators | MERCK PATENT GmbH (DE) | 1986-08-27 | — | — | EP | disclosed |