Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | NMBR | P28336 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522368 | 0.93 | REN (0.54) | RENFNTAPGGT1BNMBR | |
| SCHEMBL10571943 | 0.88 | REN (0.66) | RENFNTAPGGT1B | |
| SCHEMBL29486802 | 0.85 | REN (0.64) | REN | |
| SCHEMBL10825069 | 0.85 | REN (0.64) | REN | |
| SCHEMBL10571770 | 0.85 | REN (0.63) | RENFNTAPGGT1B | |
| SCHEMBL10872017 | 0.84 | HRH4 (0.50) | HRH4MME | |
| SCHEMBL7758645 | 0.81 | MEN1 (0.60) | — | |
| SCHEMBL10570967 | 0.80 | HRH4 (0.47) | RENHRH4MME | |
| SCHEMBL10570975 | 0.80 | HRH4 (0.47) | RENHRH4MME | |
| SCHEMBL7291021 | 0.80 | KMT2A (0.57) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190891-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |