Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570975 | 0.96 | HRH4 (0.47) | HRH4LTA4HKMT2AMEN1MMP2 | |
| SCHEMBL10570967 | 0.96 | HRH4 (0.47) | HRH4LTA4HKMT2AMEN1MMP2 | |
| SCHEMBL10522999 | 0.93 | KMT2A (0.44) | HRH4LTA4HKMT2AMEN1MMP2 | |
| SCHEMBL10522366 | 0.93 | HRH4 (0.42) | HRH4MMP2MMP8MMP9PTPN1 | |
| SCHEMBL10522100 | 0.91 | HRH4 (0.43) | HRH4LTA4HKMT2AMEN1MMP2 | |
| SCHEMBL8487755 | 0.89 | HRH4 (0.48) | HRH4CYP3A4 | |
| SCHEMBL8487752 | 0.89 | HRH4 (0.48) | HRH4CYP3A4 | |
| SCHEMBL10878220 | 0.89 | MEN1 (0.41) | HRH4LTA4HKMT2AMEN1MMP2 | |
| SCHEMBL10521511 | 0.89 | MMP2 (0.46) | MMP2MMP8MMP9 | |
| SCHEMBL10571933 | 0.88 | REN (0.49) | MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190891-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |