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SCHEMBL10872340

SCHEMBL10872340

CC(NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(N)CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.48
▸ NPY4R P50391 12/20 0.47
▸ NPY1R P25929 7/20 0.47
▸ NPY5R Q15761 7/20 0.47
▸ NPY2R P49146 4/20 0.47
▸ EGFR P00533 1/20 0.42
▸ BACE1 P56817 1/20 0.41
▸ NOD1 Q9Y239 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7447936 1.00 FOLH1 (0.48) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL7447958 1.00 FOLH1 (0.48) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL10872360 1.00 FOLH1 (0.48) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL29392656 0.96 FOLH1 (0.45) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL10871602 0.96 NPY4R (0.47) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL10871591 0.96 NPY4R (0.47) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL9484017 0.96 NPY4R (0.47) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL9484006 0.96 NPY4R (0.47) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL31539991 0.95 FOLH1 (0.46) FOLH1NPY4RNPY1RNPY5RNPY2R
SCHEMBL30807970 0.95 FOLH1 (0.46) FOLH1NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0206783-A2 Expression and secretion of polypeptides from saccharomyces cerevisiae The Salk Institute Biotechnology Industrial Associates, Inc. (US) 1986-12-30 — — EP disclosed
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