Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | NPY4R | P50391 | 12/20 | 0.47 |
| ▸ | NPY1R | P25929 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | NPY2R | P49146 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447958 | 1.00 | FOLH1 (0.48) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10872360 | 1.00 | FOLH1 (0.48) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10872340 | 1.00 | FOLH1 (0.48) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29392656 | 0.96 | FOLH1 (0.45) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10871602 | 0.96 | NPY4R (0.47) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10871591 | 0.96 | NPY4R (0.47) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9484017 | 0.96 | NPY4R (0.47) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9484006 | 0.96 | NPY4R (0.47) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31539991 | 0.95 | FOLH1 (0.46) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30807970 | 0.95 | FOLH1 (0.46) | FOLH1NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399107-B1 | GLYCOSAMINOGLYCAN(GAG); TOPICALLY ADMINISTERING GENISTEIN SODIUM METAVANADATE AND/OR STAUROSPORINE PRIOR TO, DURING OR AFTER LASER SURGERY TO PREVENT CORNEAL CLOUDING | ALCON LABORATORIES, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000037072-A1 | USE OF INHIBITORS OF GAG SYNTHESIS FOR THE TREATMENT OF CORNEAL HAZE | ALCON LABORATORIES, INC. (US) | 2000-06-29 | — | — | WO | disclosed |