Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.47 |
| ▸ | NPY1R | P25929 | 8/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | NPY2R | P49146 | 4/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871602 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL9484006 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL10871591 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL29985369 | 0.98 | NPY4R (0.45) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL29905986 | 0.98 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL7447958 | 0.96 | FOLH1 (0.48) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL10872360 | 0.96 | FOLH1 (0.48) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL7447936 | 0.96 | FOLH1 (0.48) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL10872340 | 0.96 | FOLH1 (0.48) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL30938814 | 0.95 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258302-A | DNA for expression of aprotinin in methylotrophic yeast cells | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0547171-A1 | PRODUCTION OF HUMAN LYSOZYME IN METHYLOTROPHIC YEAST CELLS AND EFFICIENT SECRETION THEREFROM | THE SALK INSTITUTE BIOTECHNOLOGY INDUSTRIAL ASSOCIATES, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5102789-A | Genetic engineering; replacing one or more amino acids by other to inhibit the secretion of gastric acid | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1992-04-07 | — | — | US | disclosed |
| WO-1992004441-A1 | PRODUCTION OF HUMAN LYSOZYME IN METHYLOTROPHIC YEAST CELLS AND EFFICIENT SECRETION THEREFROM | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992001048-A1 | PRODUCTION OF APROTININ IN METHYLOTROPHIC YEAST CELLS | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1992-01-23 | — | — | WO | disclosed |
| EP-0206783-A2 | Expression and secretion of polypeptides from saccharomyces cerevisiae | The Salk Institute Biotechnology Industrial Associates, Inc. (US) | 1986-12-30 | — | — | EP | disclosed |