Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319294 | 0.94 | HPGD (0.61) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10871420 | 0.89 | HPGD (0.55) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10870757 | 0.89 | HPGD (0.73) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10871883 | 0.84 | HPGD (0.50) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10870481 | 0.84 | KMT2A (0.66) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10874045 | 0.84 | HPGD (0.66) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10872144 | 0.84 | HPGD (0.50) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11097930 | 0.83 | MAPK1 (0.52) | HPGDLMNAALDH1A1MAPK1MAPT | |
| SCHEMBL20082815 | 0.83 | CNR1 (0.46) | LMNAALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL10871424 | 0.82 | LMNA (0.48) | HPGDLMNAL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192167-A1 | Use of thio-substitued ketones as photoinitiators | MERCK PATENT GmbH (DE) | 1986-08-27 | — | — | EP | disclosed |