SCHEMBL1087322

SCHEMBL1087322

Cc1ccc(C2=CC(=O)NC2=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
PTGS2 P35354 1/20 0.40
HPGD P15428 4/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
RGS4 P49798 1/20 0.36
ALOX5 P09917 1/20 0.36
PIM1 P11309 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
NOTUM Q6P988 1/20 0.35
MAPT P10636 3/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27993865 0.98 ALDH1A1 (0.41) ALDH1A1PTGS2HPGDCYP2D6CYP2C9
Ammonia Solution, Strong SCHEMBL27993532 0.98 ALDH1A1 (0.41) ALDH1A1PTGS2HPGDCYP2D6CYP2C9
SCHEMBL31510365 0.89 MAPT (0.40) ALDH1A1PTGS2HPGDCYP2C9CYP2C19
SCHEMBL448198 0.89 BACE1 (0.32) CCR6
SCHEMBL16668754 0.87 HSD17B3 (0.34) MAOAMAOB
SCHEMBL2712453 0.81 HAO1 (0.42) ALDH1A1LMNAMEN1KMT2APIM1
SCHEMBL1232781 0.79 RECQL (0.41) ALDH1A1PTGS2HPGDLMNAMEN1
SCHEMBL7800993 0.79 ALDH1A1 (0.32) ALDH1A1NOTUM
SCHEMBL3795697 0.79 CYP3A4 (0.40) ALDH1A1ALOX15HSD17B10MEN1KMT2A
SCHEMBL552048 0.79 MGAM (0.43) PTGS2HPGDEGFRTDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
CN-110041463-A A kind of modified tamarind gum polymer and its preparation method and application 福建清源科技有限公司 2019-07-23 CN claimed
CN-110003224-A The p-methylphenyl substituted maleimide amine of N- containing pyrrazole structure α-terpinene cycloaddition derivative and its preparation method and application 绍兴文理学院元培学院 2019-07-12 CN claimed
CN-109280542-A High-temperature-resistant gel plugging agent and preparation method and application thereof 中国石油天然气股份有限公司 2019-01-29 CN claimed
CN-105694385-B A kind of raising polycondensation physical performance and the master batch of melt strength and preparation method thereof 上海富元塑胶科技有限公司 2018-11-23 CN claimed
CN-105906632-B Pyrazoles N- p-methylphenyl maleimide derivatives containing chromone structure and preparation method and application 绍兴文理学院 2018-05-29 CN claimed
CN-106832909-A A kind of high-dimensional stability PA/ABS alloys and preparation method 上海杰事杰新材料(集团)股份有限公司 2017-06-13 CN claimed
CN-106502051-A Negative light-sensitive resin combination and the photo-curable pattern formed by which 东友精细化工有限公司 2017-03-15 CN claimed
CN-106280205-A A kind of heat-proof ABS compositions and preparation method thereof 上海华谊聚合物有限公司 2017-01-04 CN claimed
CN-102807752-B PA6 (Polyamide 6)/ABS (Acrylonitrile Butadiene Styrene) alloy and preparation method thereof HEFEI GENIUS NEW MAT CO LTD 2015-04-15 CN claimed
CN-101821352-B Adhesive and connection structure using same HITACHI CHEMICAL CO LTD 2013-06-19 CN claimed
CN-101212065-B Non-aqueous electrolyte containing maleimide additive and alkali metal group secondary battery comprising the same IND TECH RES INST 2011-08-24 CN claimed
US-7825188-B2 Thermoplastic elastomer with acyloxyphenyl hard block segment DESIGNER MOLECULES, INC. (US) 2010-11-02 US claimed
CN-101212065-A Non-aqueous electrolyte containing maleimide additive and alkali metal group secondary battery comprising the same IND TECH RES INST (CN) 2008-07-02 CN claimed
WO-2008077141-A1 RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-06-26 WO claimed
US-20080146738-A1 RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. 2008-06-19 US claimed
EP-0253624-B1 ACRYLIC MODIFIED N-ARYLMALEIMIDE COPOLYMER MOLDING COMPOSITION ARCO CHEMICAL TECHNOLOGY, INC. (US) 1992-03-11 EP claimed
EP-0331975-A1 Thermoplastic resin composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-09-13 EP claimed
EP-0253624-A2 Acrylic modified N-arylmaleimide copolymer molding composition ARCO CHEMICAL TECHNOLOGY, INC. (US) 1988-01-20 EP claimed
US-4701493-A EMULSION POLYMERIZATION ATLANTIC RICHFIELD COMPANY (US) 1987-10-20 US claimed