SCHEMBL448198

SCHEMBL448198

O=C1C=C(c2ccc(C3=CC(=O)NC3=O)cc2)C(=O)N1

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.32
HSD17B3 P37058 1/20 0.31
GSK3B P49841 2/20 0.31
HAO1 Q9UJM8 1/20 0.31
GSK3A P49840 1/20 0.30
CCR6 P51684 1/20 0.30
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16668754 0.97 HSD17B3 (0.34) BACE1HSD17B3HAO1PRKD3PRKCG
SCHEMBL2712453 0.91 HAO1 (0.42) HAO1
SCHEMBL28171444 0.89 MAPT (0.38) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL552048 0.89 MGAM (0.43) BACE1GSK3BPRKD3PRKCGPRKCB
SCHEMBL27812998 0.89 TGM2 (0.33)
SCHEMBL1232781 0.89 RECQL (0.41) GSK3B
SCHEMBL28438497 0.89 HSD17B3 (0.47) BACE1HSD17B3PRKD3PRKCGPRKCB
SCHEMBL1087322 0.89 ALDH1A1 (0.42) CCR6
SCHEMBL3795697 0.89 CYP3A4 (0.40) PRKD3PRKCGPRKCBPRKCAPRKCH
Ammonia Solution, Strong SCHEMBL27900928 0.89 HAO1 (0.41) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040750-A Preparation method of high-temperature-resistant engineering plastic amino-terminated polyaryl ether nitrile toughened BT resin 四川金象赛瑞化工股份有限公司 2025-05-27 CN claimed
CN-120005236-A Stimulus-responsive crosslinked polyamide, preparation method thereof and stimulus response method 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-117304679-B 4D printing polyurethane-based hydrogel material and preparation method and application thereof 中国科学院深圳先进技术研究院 2025-03-18 CN claimed
CN-119431678-A Flame retardant composition 长春人造树脂厂股份有限公司 2025-02-14 CN claimed
CN-119192473-A Imidazolyl polymeric ionic liquid, and preparation method and application thereof 荆楚理工学院 2024-12-27 CN claimed
CN-119173556-A Self-healing polymers 布鲁塞尔自由大学 2024-12-20 CN claimed
WO-2024258063-A1 METHOD FOR MANUFACTURING BIODEGRADABLE FILTER MATERIAL, BIODEGRADABLE FILTER MATERIAL, AIR PURIFICATION FILTER COMPRISING SAME, AND HOME APPLIANCE 삼성전자 주식회사 2024-12-19 WO claimed
CN-117447782-B Composite material for lithium battery diaphragm and manufacturing method thereof 江西昊泽光学膜科技有限公司 2024-06-25 CN claimed
CN-118239462-A Hard carbon negative electrode material and preparation method and application thereof 湖南中科星城石墨有限公司 2024-06-25 CN claimed
CN-115895257-B Method for improving surface quality of bismaleimide resin condensate 中国航发北京航空材料研究院 2024-06-21 CN claimed
EP-2045102-A1 MULTILAYER BODY, METHOD FOR PRODUCING THE SAME, INNER LINER FOR PNEUMATIC TIRE AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2009-04-08 EP claimed
EP-2036743-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2009-03-18 EP claimed
US-20080124523-A1 Laminate, Method for Producing the Same and Tire Using the Same BRIDGESTONE CORPORATION (JP) 2008-05-29 US claimed
EP-1818187-A1 LAMINATE, METHOD FOR PRODUCING THE SAME AND TIRE USING THE SAME Bridgestone Corporation (JP) 2007-08-15 EP claimed
EP-1534734-A1 METHOD FOR THE SYNTHESIS AND SELECTIVE BIOCATALYTIC MODIFICATION OF PEPTIDES, PEPTIDE MIMETICS AND PROTEINS BOEHRINGER MANNHEIM GMBH (DE) 2005-06-01 EP claimed
WO-2004024751-A1 METHOD FOR THE SYNTHESIS AND SELECTIVE BIOCATALYTIC MODIFICATION OF PEPTIDES, PEPTIDE MIMETICS AND PROTEINS F. HOFFMANN-LA ROCHE AG (CH) 2004-03-25 WO claimed
EP-0398533-B1 Poly(arylene sulfide) resin composition TOTO KASEI KK (JP) 1997-07-02 EP claimed
US-5227429-A Butadiene-styrene block polymer, maleimide crosslinking agent TOHPREN CO., LTD. (JP) 1993-07-13 US claimed
EP-0398533-A2 Poly(arylene sulfide) resin composition Tohpren Co., Ltd. (JP) 1990-11-22 EP claimed
US-4143029-A HEXAKIS/ALKOXYMETHYL/MELAMINE, A TRIHYDROCARBYLCARBONYL MELAMINE, AND A BIS/MALEIMIDE UNIROYAL, INC. (US) 1979-03-06 US claimed