Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875323 | 0.87 | SLC6A2 (0.30) | SLC6A2 | |
| SCHEMBL9519463 | 0.81 | TP53 (0.30) | — | |
| SCHEMBL9518181 | 0.70 | TP53 (0.32) | — | |
| SCHEMBL10873297 | 0.66 | SLC6A2 (0.30) | SLC6A2 | |
| SCHEMBL10874046 | 0.66 | — | — | |
| SCHEMBL10871210 | 0.65 | P2RX4 (0.33) | — | |
| SCHEMBL8439081 | 0.65 | P2RX4 (0.33) | — | |
| SCHEMBL10160091 | 0.65 | CHRNB2 (0.32) | — | |
| SCHEMBL16064970 | 0.64 | ALDH1A1 (0.44) | — | |
| SCHEMBL31623253 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181926-A1 | SUBSTITUTED CUBANES | UNIVERSITY PATENTS, INC. (US) | 1986-05-28 | — | — | EP | disclosed |
| WO-1985005357-A1 | SUBSTITUTED CUBANES | UNIVERSITY PATENTS, INC. (US) | 1985-12-05 | — | — | WO | disclosed |