Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872909 | 0.93 | MAPT (0.58) | TDP1RECQLRORCALDH1A1MAPT | |
| SCHEMBL10874979 | 0.86 | TDP1 (0.70) | TDP1RECQLHPGDRORCALDH1A1 | |
| SCHEMBL9795781 | 0.85 | ALDH1A1 (0.53) | TDP1RECQLHPGDRORCALDH1A1 | |
| SCHEMBL10876354 | 0.84 | TDP1 (0.76) | TDP1RECQLHPGDRORCALDH1A1 | |
| SCHEMBL6152534 | 0.83 | HRH3 (0.55) | TDP1RECQLRORCALDH1A1LMNA | |
| SCHEMBL11582978 | 0.83 | EPHX1 (0.52) | FAAHLMNACYP1A2SMN1; SMN2CYP2C9 | |
| SCHEMBL8484560 | 0.83 | EPHX1 (0.52) | FAAHLMNACYP1A2SMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10873126 | 0.83 | TDP1 (0.74) | TDP1RECQLHPGDRORCALDH1A1 | |
| SCHEMBL6157997 | 0.82 | ALDH1A1 (0.48) | TDP1RECQLRORCALDH1A1MAPT | |
| SCHEMBL13637511 | 0.82 | TDP1 (0.62) | TDP1RECQLHPGDRORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142788-B1 | PROCESS FOR THE PREPARATION OF PURE 3-ACETYLAMINO-ANILINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-24 | — | — | EP | disclosed |
| US-4540815-A | Process for the preparation of pure 3-acetylamino-anilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0142788-A1 | Process for the preparation of pure 3-acetylamino-aniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-29 | — | — | EP | disclosed |