SCHEMBL6157997

SCHEMBL6157997

CC[N+](C)(CC)CCOc1ccc(NC(C)=O)cc1NC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
RORC P51449 1/20 0.48
RECQL P46063 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPT P10636 4/20 0.43
HSD17B10 Q99714 1/20 0.42
TERT O14746 2/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
LMNA P02545 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
HTT P42858 2/20 0.40
MLNR O43193 1/20 0.40
NR1I2 O75469 1/20 0.40
NR3C1 P04150 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL7740639 0.99 ALDH1A1 (0.47) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL10872909 0.84 MAPT (0.58) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL10874142 0.82 TDP1 (0.54) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL10874979 0.81 TDP1 (0.70) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL9795781 0.80 ALDH1A1 (0.53) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL4667768 0.79 GAA (0.40) ALDH1A1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL6152534 0.78 HRH3 (0.55) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL6157990 0.76 ALDH1A1 (0.50) ALDH1A1TDP1RORCRECQLCYP1A2
SCHEMBL4667682 0.75 CYP19A1 (0.60) ALDH1A1TDP1MAPTKMT2AMEN1
SCHEMBL7163975 0.75 LMNA (0.48) ALDH1A1MAPTHSD17B10KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064252-B1 OXIDATION DYEING COMPOSITIONS CONTAINING A CATIONIC COUPLING AGENT, NOVEL CATIONIC COUPLING AGENTS OREAL (FR) 2005-06-15 EP disclosed
EP-1064252-A1 OXIDATION DYEING COMPOSITIONS CONTAINING A CATIONIC COUPLING AGENT, NOVEL CATIONIC COUPLING AGENTS L'OREAL (FR) 2001-01-03 EP disclosed
WO-1999048856-A1 OXIDATION DYEING COMPOSITIONS CONTAINING A CATIONIC COUPLING AGENT, NOVEL CATIONIC COUPLING AGENTS L'OREAL (FR) 1999-09-30 WO disclosed