Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130204 | 0.88 | HPGD (0.54) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL12171026 | 0.82 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL28823518 | 0.75 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2HPGDGAAPOLB | |
| SCHEMBL10873185 | 0.74 | IDO1 (0.56) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL10873018 | 0.74 | MAPT (0.53) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 | |
| Hydrochloric Acid SCHEMBL10888899 | 0.73 | IDO1 (0.54) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL28870091 | 0.73 | AMY1A (0.54) | L3MBTL1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL10873813 | 0.73 | GAA (0.52) | SMN1; SMN2HPGDGAAMEN1KMT2A | |
| SCHEMBL5713554 | 0.73 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL28039858 | 0.72 | HPGD (0.45) | L3MBTL1SMN1; SMN2HPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200345-A2 | Anti-allergic or anti-inflammatory substituted (hetero)-aralkylamino-ortho-phenols | BEECHAM GROUP PLC (GB) | 1986-11-05 | — | — | EP | claimed |
| EP-0200345-A2 | Anti-allergic or anti-inflammatory substituted (hetero)-aralkylamino-ortho-phenols | BEECHAM GROUP PLC (GB) | 1986-11-05 | — | — | EP | disclosed |