Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874268 | 1.00 | MAPT (0.44) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL10875461 | 0.99 | MAPT (0.43) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL10875457 | 0.99 | MAPT (0.43) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Nitric Acid SCHEMBL10874977 | 0.92 | MAPT (0.46) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Nitric Acid SCHEMBL10874973 | 0.92 | MAPT (0.46) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL10917952 | 0.88 | LMNA (0.40) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL10917946 | 0.88 | LMNA (0.40) | MAPTCYP3A4GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL10878736 | 0.82 | CYP19A1 (0.36) | MAPTCYP3A4ALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL10878732 | 0.82 | CYP19A1 (0.36) | MAPTCYP3A4ALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL10879898 | 0.82 | GABRA1 (0.46) | MAPTCYP3A4GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049913-B1 | NEW ETHENYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; INTERMEDIATES, USEFUL IN THEIR PREPARATION AND A PROCESS FOR THE PREPARATION THEREOF | GIST-BROCADES N.V. (NL) | 1986-03-19 | — | — | EP | claimed |
| EP-0049913-A2 | New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof | GIST-BROCADES N.V. (NL) | 1982-04-21 | — | — | EP | claimed |
| EP-0049913-B1 | NEW ETHENYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; INTERMEDIATES, USEFUL IN THEIR PREPARATION AND A PROCESS FOR THE PREPARATION THEREOF | GIST-BROCADES N.V. (NL) | 1986-03-19 | — | — | EP | disclosed |