Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537050 | 0.81 | PTGS2 (0.49) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5421011 | 0.78 | PTGS2 (0.46) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5783938 | 0.74 | CYP3A4 (0.35) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL17924772 | 0.73 | GABRA1 (0.40) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL1533221 | 0.73 | TAAR1 (0.50) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5629303 | 0.72 | PTGS2 (0.60) | XDHPTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL15756039 | 0.72 | GABRA1 (0.35) | PTGS2GABRA1GABRB2AKR1B1L3MBTL1 | |
| SCHEMBL11817910 | 0.72 | GABRA1 (0.52) | XDHALDH1A1KMT2AMEN1MAPT | |
| Allylbenzene SCHEMBL10325179 | 0.71 | MAOB (0.60) | XDHALDH1A1KMT2AMEN1MAPT | |
| Allylbenzene SCHEMBL2478260 | 0.71 | MAOB (0.60) | XDHALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205402-A2 | 2,6-Disubstituted-4-epoxypropylphenyl glycidyl ethers, and their preparation | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |