Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872658 | 0.93 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10872655 | 0.87 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10874710 | 0.86 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10874415 | 0.85 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10872692 | 0.85 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10872656 | 0.85 | SMN1; SMN2 (0.52) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10872664 | 0.81 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10859301 | 0.81 | RAB9A (0.50) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10955351 | 0.79 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL10909174 | 0.79 | MAPT (0.48) | LMNARAB9AMAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177591-A1 | NOVEL PHOSPHINATES | SANDOZ AG (CH) | 1986-04-16 | — | — | EP | disclosed |
| WO-1985004661-A1 | NOVEL PHOSPHINATES | SANDOZ AG (CH) | 1985-10-24 | — | — | WO | disclosed |