SCHEMBL10874811

SCHEMBL10874811

O=S(=O)(O)c1cc(O)c(N=Nc2ccc(O)cc2O)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NSD2 O96028 2/20 1.00
▸ MMP14 P50281 2/20 1.00
▸ CASP6 P55212 2/20 1.00
▸ MPL P40238 16/20 0.70
▸ CTRC Q99895 2/20 0.69
▸ CYP1A2 P05177 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ CSNK2A1 P68400 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ PRMT1 Q99873 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16853116 1.00 NSD2 (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL10896468 0.87 NSD2 (0.78) NSD2MMP14CASP6MPLCTRC
SCHEMBL3346557 0.86 NSD2 (0.76) NSD2MMP14CASP6MPLCTRC
SCHEMBL4596970 0.82 MPL (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL4596966 0.82 MPL (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL7252970 0.80 MPL (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL7252973 0.80 MPL (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL12459388 0.80 MPL (0.78) NSD2MMP14CASP6MPLCTRC
SCHEMBL31236789 0.79 MPL (1.00) NSD2MMP14CASP6MPLCTRC
SCHEMBL263651 0.79 MPL (1.00) NSD2MMP14CASP6MPLCTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0009411-B2 PHOTOGRAPHIC RECORDING MATERIAL CONTAINING POLYMERS WHICH COORDINATE WITH METAL IONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-11-26 — — EP disclosed
EP-0009411-B1 PHOTOGRAPHIC RECORDING MATERIAL CONTAINING POLYMERS WHICH COORDINATE WITH METAL IONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-06-01 — — EP disclosed
US-4299895-A Photographic elements containing polymers which coordinate with metal ions EASTMAN KODAK COMPANY (US) 1981-11-10 — — US disclosed
US-4239847-A Photographic elements containing polymers which coordinate with metal ions EASTMAN KODAK COMPANY (US) 1980-12-16 — — US disclosed
EP-0009411-A2 Photographic recording material containing polymers which coordinate with metal ions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-02 — — EP disclosed
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