Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.76 |
| ▸ | MMP14 | P50281 | 1/20 | 0.76 |
| ▸ | CASP6 | P55212 | 1/20 | 0.76 |
| ▸ | MPL | P40238 | 13/20 | 0.74 |
| ▸ | CTRC | Q99895 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345861 | 0.87 | MPL (0.61) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL10896468 | 0.87 | NSD2 (0.78) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL10874811 | 0.86 | NSD2 (1.00) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL16853116 | 0.86 | NSD2 (1.00) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL4596966 | 0.84 | MPL (1.00) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL4596970 | 0.84 | MPL (1.00) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL30049470 | 0.83 | CTRB1 (0.73) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL5701120 | 0.83 | CTRB1 (0.73) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL6763835 | 0.83 | CTRB1 (0.73) | NSD2MMP14CASP6MPLCTRC | |
| SCHEMBL28551711 | 0.83 | CYP1A2 (0.70) | NSD2MMP14CASP6MPLCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | claimed |
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | disclosed |