Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702853 | 0.84 | ADORA2A (0.55) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10515313 | 0.84 | ADORA2A (0.51) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10514725 | 0.80 | ADORA2A (0.54) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14669191 | 0.78 | CYP3A4 (0.70) | ADORA2AADORA1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL10515035 | 0.77 | AHCY (0.67) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14669211 | 0.76 | CYP3A4 (0.58) | CYP3A4CYP2D6 | |
| SCHEMBL14669084 | 0.76 | CYP3A4 (0.58) | CYP3A4CYP2D6 | |
| SCHEMBL16131312 | 0.76 | CYP3A4 (0.58) | CYP3A4CYP2D6 | |
| SCHEMBL4364344 | 0.75 | ADORA2A (0.70) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6363452 | 0.75 | AHCY (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |