SCHEMBL108757

SCHEMBL108757

COCc1cc(N)ccc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
GAA P10253 4/20 0.44
HTT P42858 2/20 0.44
MAPK1 P28482 2/20 0.44
TSHR P16473 2/20 0.44
CASP1 P29466 2/20 0.38
CYP19A1 P11511 4/20 0.38
PRKCI P41743 1/20 0.37
ALDH1A1 P00352 7/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ACHE P22303 1/20 0.36
LMNA P02545 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
CASP7 P55210 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19899827 1.00 MAPT (0.44) MAPTGAAHTTMAPK1TSHR
SCHEMBL29354986 1.00 MAPT (0.44) MAPTGAAHTTMAPK1TSHR
Bromide SCHEMBL26108834 0.98 MAPT (0.42) MAPTGAAHTTMAPK1TSHR
Hydrochloric Acid SCHEMBL7132484 0.98 MAPT (0.42) MAPTGAAHTTMAPK1TSHR
Hydrochloric Acid SCHEMBL6256039 0.98 MAPT (0.42) MAPTGAAHTTMAPK1TSHR
SCHEMBL4799943 0.92 GAA (0.39) MAPTGAAHTTMAPK1TSHR
Sulfuric Acid SCHEMBL29835982 0.89 ALDH1A1 (0.49) MAPTGAAHTTMAPK1TSHR
Sulfuric Acid SCHEMBL5230762 0.89 ALDH1A1 (0.49) MAPTGAAHTTMAPK1TSHR
SCHEMBL1887779 0.84 MAPT (0.50) MAPTGAAHTTMAPK1TSHR
SCHEMBL19970632 0.83 PRKCI (0.38) MAPTGAAHTTMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3411 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
CN-122074072-A Novel and cost-effective polycondensation of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2026-05-22 CN claimed
WO-2026102602-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2026-05-21 WO claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
WO-2026102601-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2026-05-21 WO claimed
US-20260137607-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL LOREAL (FR) 2026-05-21 US claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
US-12622853-B2 Composition comprising a particular oxidation dye precursor and a particular amino silicone L'OREAL (FR) 2026-05-12 US claimed
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
US-20030172471-A1 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-09-18 US claimed
US-20030093867-A1 Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-05-22 US claimed
US-6558433-B2 Oxidation hair dye WELLA AG (DE) 2003-05-06 US claimed
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same Wella GmbH (DE) 2003-03-06 US claimed
US-6503282-B1 Composition for coloring keratin fibers based on a developer-coupler combination characterized in that it contains as the coupler 3-(2,4-diaminophenoxy)-1-propanol and as the developer ring and having general formula (I) WELLA AKTIENGESELLSCHAFT (DE) 2003-01-07 US claimed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 US claimed
EP-1166749-A2 Composition and process for dyeing keratinic fibres Wella Aktiengesellschaft (DE) 2002-01-02 EP claimed
EP-1158954-A1 MEANS AND METHOD FOR DYING KERATINIC FIBRES Wella Aktiengesellschaft (DE) 2001-12-05 EP claimed
WO-2001051019-A1 MEANS AND METHOD FOR DYING KERATINIC FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2001-07-19 WO claimed
EP-1103542-A2 Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres Wella Aktiengesellschaft (DE) 2001-05-30 EP claimed