SCHEMBL19970632

SCHEMBL19970632

COCc1cc(N)ccc1N.Cc1c(O)cccc1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.38
ACHE P22303 1/20 0.37
TSHR P16473 2/20 0.37
CASP1 P29466 1/20 0.37
PDE10A Q9Y233 1/20 0.37
MAPT P10636 3/20 0.37
PRKCE Q02156 2/20 0.37
MYLK Q15746 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
PLAU P00749 1/20 0.37
MEN1 O00255 1/20 0.37
PRKCG P05129 1/20 0.37
PRKCA P17252 1/20 0.37
APEX1 P27695 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108757 0.83 MAPT (0.44) PRKCIACHETSHRCASP1MAPT
SCHEMBL29354986 0.83 MAPT (0.44) PRKCIACHETSHRCASP1MAPT
SCHEMBL19899827 0.83 MAPT (0.44) PRKCIACHETSHRCASP1MAPT
SCHEMBL1981861 0.83 PRKCI (0.39) PRKCIACHETSHRCASP1PDE10A
Hydrochloric Acid SCHEMBL7132484 0.82 MAPT (0.42) PRKCIACHETSHRCASP1MAPT
Hydrochloric Acid SCHEMBL6256039 0.82 MAPT (0.42) PRKCIACHETSHRCASP1MAPT
Bromide SCHEMBL26108834 0.82 MAPT (0.42) PRKCIACHETSHRCASP1MAPT
SCHEMBL19307703 0.80 KDM4E (0.45) PRKCIACHETSHRCASP1MAPT
Sulfuric Acid SCHEMBL29835982 0.78 ALDH1A1 (0.49) PRKCIACHETSHRCASP1MAPT
Sulfuric Acid SCHEMBL5230762 0.78 ALDH1A1 (0.49) PRKCIACHETSHRCASP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3773923-B1 HAIR TREATMENT COMPOSITIONS, SYSTEMS, DEVICES AND METHODS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2023-10-04 EP disclosed
US-11628127-B2 Composition for lightening or dyeing keratin fibers with a low amount of oxidizing agent WELLA OPERATIONS US, LLC (US) 2023-04-18 US disclosed
US-11596216-B2 Hair treatment compositions, systems, devices and methods WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2023-03-07 US disclosed
EP-3773923-A1 HAIR TREATMENT COMPOSITIONS, SYSTEMS, DEVICES AND METHODS HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-02-17 EP disclosed
US-20210037944-A1 HAIR TREATMENT COMPOSITIONS, SYSTEMS, DEVICES AND METHODS HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-02-11 US disclosed
WO-2019199779-A1 HAIR TREATMENT COMPOSITIONS, SYSTEMS, DEVICES AND METHODS MUNIZ DENA (US) 2019-10-17 WO disclosed
US-20190224088-A1 COMPOSITION FOR LIGHTENING OR DYEING KERATIN FIBERS WITH A LOW AMOUNT OF OXIDIZING AGENT WELLA OPERATIONS US, LLC 2019-07-25 US disclosed
WO-2018053177-A1 COMPOSITION FOR LIGHTENING OR DYEING KERATIN FIBERS WITH A LOW AMOUNT OF OXIDIZING AGENT NOXELL CORPORATION (US) 2018-03-22 WO disclosed
EP-3295924-A1 COMPOSITION FOR LIGHTENING OR DYEING KERATIN FIBERS WITH A LOW AMOUNT OF OXIDIZING AGENT The Procter and Gamble Company (US) 2018-03-21 EP disclosed