Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LGMN | Q99538 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940708 | 0.77 | HPGD (0.64) | HPGDCYP3A4LGMNADORA3ADORA2B | |
| SCHEMBL17595002 | 0.76 | LGMN (0.40) | LGMNADORA2BPOLBKMT2AGSK3A | |
| SCHEMBL23974602 | 0.73 | LGMN (0.58) | HPGDCYP3A4LGMNADORA3ADORA2B | |
| SCHEMBL19555085 | 0.73 | MAPK8 (0.66) | ADORA3ADORA2BMAPT | |
| SCHEMBL25827062 | 0.71 | CYP3A4 (0.69) | HPGDCYP3A4LGMNADORA3ADORA2B | |
| SCHEMBL8985073 | 0.71 | GSK3B (0.67) | HPGDCYP3A4PKMSMN1; SMN2MEN1 | |
| SCHEMBL4227686 | 0.71 | MAPK8 (0.49) | HPGDCYP3A4LGMNADORA3ADORA2B | |
| SCHEMBL25210999 | 0.71 | ALDH1A1 (0.76) | HPGDPKMSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL38658744 | 0.70 | KMT2A (0.56) | HPGDCYP3A4LGMNADORA3ADORA2B | |
| SCHEMBL23974605 | 0.70 | HPGD (0.57) | HPGDCYP3A4LGMNADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61145167-A | — | — | None | — | — | JP | disclosed |
| JP-S61145167-A | 1,3-DISUBSTITUTED-5-FLUORO-6-CHLOROURACIL DERIVATIVE AND ANTITUMOR AGENT | SAGAMI CHEM RES CENTER | 1986-07-02 | — | — | JP | disclosed |