Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510427 | 0.83 | HDAC8 (0.49) | HDAC8CYP19A1KCNA5SLC6A4SLC6A3 | |
| SCHEMBL24069228 | 0.77 | MEN1 (0.53) | HDAC8CYP19A1KCNA5CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28974280 | 0.77 | CYP19A1 (0.45) | HDAC8CYP19A1KCNA5SLC6A4SLC6A3 | |
| Ethylene SCHEMBL9547378 | 0.76 | HDAC8 (0.48) | HDAC8CYP19A1KCNA5SLC6A4SLC6A3 | |
| SCHEMBL20476844 | 0.75 | CYP3A4 (0.50) | CYP19A1SLC6A4SLC6A3SLC6A2CYP3A4 | |
| SCHEMBL10557447 | 0.75 | CYP19A1 (0.50) | HDAC8CYP19A1KCNA5SLC6A4SLC6A3 | |
| SCHEMBL3284710 | 0.74 | DPP4 (0.63) | KCNA5DPP4 | |
| SCHEMBL11464003 | 0.74 | CYP2C9 (0.62) | HDAC8CYP3A4CYP2D6POLB | |
| SCHEMBL10968611 | 0.73 | IDO1 (0.50) | CYP19A1SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL9547383 | 0.73 | HDAC8 (0.46) | HDAC8CYP19A1KCNA5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |