Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880334 | 0.89 | NPC1 (0.48) | CHRM2CHRM1CHRM3CYP1A2CYP2C19 | |
| SCHEMBL10874997 | 0.79 | MAPT (0.44) | HRH3CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL465562 | 0.76 | LTA4H (0.59) | ALDH1A1RAB9ANPC1LMNAALOX15 | |
| SCHEMBL10878574 | 0.76 | KDM4E (0.56) | MEN1KMT2AALDH1A1L3MBTL1ATM | |
| SCHEMBL10878193 | 0.75 | PPARA (0.45) | HRH3MEN1KMT2AALDH1A1ATM | |
| SCHEMBL9163381 | 0.75 | HPGD (0.53) | ALDH1A1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL2456964 | 0.75 | HRH3 (0.50) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL10878976 | 0.74 | LTA4H (0.43) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21595882 | 0.74 | HRH3 (0.58) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL10876242 | 0.74 | LTA4H (0.67) | CYP1A2CYP2C19MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |