Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983973 | 0.77 | SIGMAR1 (0.51) | HRH3MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2972286 | 0.75 | LTA4H (0.50) | HRH3MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21595882 | 0.75 | HRH3 (0.58) | HRH3ATMMEN1KMT2ACYP1A2 | |
| SCHEMBL10876416 | 0.75 | HRH3 (0.46) | HRH3ATMMEN1KMT2ACYP1A2 | |
| SCHEMBL23357890 | 0.74 | ATF4 (0.65) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7492782 | 0.73 | KMT2A (0.62) | MEN1KMT2AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL10829126 | 0.72 | LTA4H (0.54) | HRH3ATMMEN1KMT2ACYP1A2 | |
| SCHEMBL2980105 | 0.72 | SIGMAR1 (0.54) | HRH3MEN1KMT2AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27734857 | 0.71 | KMT2A (0.60) | MEN1KMT2AALDH1A1L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL9243344 | 0.70 | LTA4H (0.60) | HRH3ATMMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026258-B2 | Aryloxyalkylcarbamate-type derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2011-09-27 | — | — | US | disclosed |