SCHEMBL10877166

SCHEMBL10877166

CCOC(=O)CC[C@H](NC(=O)c1c(I)c(NC(C)=O)c(I)c(NC(C)=O)c1I)C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 3/20 0.40
CCKBR P32239 1/20 0.35
NOD2 Q9HC29 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DHFR P00374 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10875914 0.88 LMNA (0.41) L3MBTL1KMT2APOLBKDM4EALDH1A1
SCHEMBL10875915 0.88 LMNA (0.41) L3MBTL1KMT2APOLBKDM4EALDH1A1
SCHEMBL9816287 0.85 LMNA (0.44) L3MBTL1KMT2APOLBKDM4EALDH1A1
SCHEMBL9816290 0.83 PPID (0.43) ALDH1A1LMNASMN1; SMN2
SCHEMBL9816321 0.82 LMNA (0.40) L3MBTL1KDM4EALDH1A1LMNASMN1; SMN2
SCHEMBL9816280 0.80 LMNA (0.49) KDM4EALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL10875108 0.79 LMNA (0.44) KMT2AKDM4EALDH1A1HPGDLMNA
SCHEMBL10878174 0.78 TACR1 (0.48) L3MBTL1POLB
SCHEMBL10875653 0.77 CYP1A2 (0.44) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL11012483 0.76 FOLH1 (0.49) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4607123-A X-RAY CONTRAST AGENTS DR. FRANZ KOHLER CHEMIE GMBH (DE) 1986-08-19 US disclosed