Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816287 | 0.87 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10875915 | 0.85 | LMNA (0.41) | PPIDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10875914 | 0.85 | LMNA (0.41) | PPIDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9816280 | 0.84 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL9816296 | 0.84 | ALDH1A1 (0.53) | LMNAFPR2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9816321 | 0.84 | LMNA (0.40) | PPIDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10877166 | 0.83 | L3MBTL1 (0.52) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10878174 | 0.80 | TACR1 (0.48) | FPR2 | |
| SCHEMBL332859 | 0.76 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5813383 | 0.74 | ALDH1A1 (0.60) | PPIDLMNATAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4607123-A | X-RAY CONTRAST AGENTS | DR. FRANZ KOHLER CHEMIE GMBH (DE) | 1986-08-19 | — | — | US | disclosed |
| EP-0153992-A2 | Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use | Dr. Franz Köhler Chemie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |