Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601735 | 0.85 | LMNA (0.41) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL131802 | 0.81 | LMNA (0.54) | CA1LMNAMMP1MMP2MMP3 | |
| SCHEMBL11719240 | 0.81 | LMNA (0.54) | LMNAMAPTMAPK1 | |
| Ammonia Solution, Strong SCHEMBL28576941 | 0.79 | LMNA (0.52) | CA1LMNATDP1MAPT | |
| Hydrochloric Acid SCHEMBL30807186 | 0.79 | LMNA (0.52) | CA1LMNATDP1MAPT | |
| SCHEMBL1171148 | 0.79 | — | — | |
| SCHEMBL27920846 | 0.79 | LMNA (0.52) | CA1LMNATDP1MAPT | |
| SCHEMBL21916350 | 0.78 | LMNA (0.32) | LMNA | |
| SCHEMBL10874983 | 0.77 | CA1 (0.44) | CA1LMNAMMP1MMP2MMP3 | |
| SCHEMBL21346556 | 0.77 | CA1 (0.44) | CA1LMNAMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093548-B1 | CEPHALOSPORIN DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4497809-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-02-05 | — | — | US | disclosed |
| EP-0093548-A2 | Cephalosporin derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |