SCHEMBL11601735

SCHEMBL11601735

CC(Cl)OC(=O)CCC(=O)OC(C)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
TSHR P16473 5/20 0.41
MAPT P10636 3/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA1A P35348 1/20 0.32
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
BLM P54132 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14661595 0.91 EGLN1 (0.45) LMNATSHRMAPK1MMP1MMP2
SCHEMBL11719240 0.90 LMNA (0.54) LMNATSHRMAPTMAPK1ALDH1A1
SCHEMBL1171148 0.87
SCHEMBL24360015 0.87 CYP1A2 (0.45) LMNATSHRALDH1A1GAAKMT2A
SCHEMBL10877201 0.85 CA1 (0.44) LMNAMAPTMAPK1MMP1MMP2
SCHEMBL24360329 0.85 CYP2D6 (0.37) LMNATSHR
SCHEMBL11800177 0.84 LMNA (0.59) LMNAMAPTMAPK1ALDH1A1MEN1
SCHEMBL9065292 0.83 MGAM (0.38) LMNATSHRMMP1MMP2MMP3
SCHEMBL27709776 0.82 MEN1 (0.39) LMNAMEN1KMT2A
SCHEMBL5507831 0.82 LMNA (0.68) LMNATSHRMAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333943-A Preparation method of HDPE corrugated pipe material for sewage pipe 安徽海东环保科技有限公司 2020-06-26 CN claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
CN-115845152-A Medical instrument 元心科技(深圳)有限公司 2023-03-28 CN disclosed
CN-109803693-B Medical instrument 元心科技(深圳)有限公司 2022-12-27 CN disclosed
CN-114644635-A Triazole tricyclic derivative and preparation method and application thereof 上海济煜医药科技有限公司 2022-06-21 CN disclosed
CN-111018861-B Pyrrolopyrimidine compounds 正大天晴药业集团股份有限公司 2021-11-19 CN disclosed
CN-111333943-A Preparation method of HDPE corrugated pipe material for sewage pipe 安徽海东环保科技有限公司 2020-06-26 CN disclosed
CN-111333943-A Preparation method of HDPE corrugated pipe material for sewage pipe 安徽海东环保科技有限公司 2020-06-26 CN disclosed
CN-111018861-A Pyrrolopyrimidine compounds 正大天晴药业集团股份有限公司 2020-04-17 CN disclosed
WO-2020071798-A1 COMPOUND, COLORED RESIN COMPOSITION, COLOR FILTER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2020-04-09 WO disclosed
US-20140243391-A1 PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-08-28 US disclosed
EP-2734531-A1 PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF Université de Strasbourg (FR) 2014-05-28 EP disclosed
WO-2013014073-A1 PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF UNIVERSITE DE STRASBOURG (FR) 2013-01-31 WO disclosed
US-4104233-A VINYL HALIDE POLYMERS, SMOKE AND FIRE RETARDANTS MONSANTO COMPANY (US) 1978-08-01 US disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243391-A1 PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF PHOSPHO1, ABHD16A, SMPD1 LMNA 1084/4885TSHR 4405/4885MAPT 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.