Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10876425 | 0.83 | AKR1C2 (0.53) | HRH3KDM4EALDH1A1HSD17B10DRD3 | |
| SCHEMBL10877223 | 0.77 | PTGS2 (0.56) | KMT2A | |
| SCHEMBL10876226 | 0.76 | PTGS2 (0.61) | — | |
| SCHEMBL10874692 | 0.75 | TLR9 (0.48) | HRH3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13503751 | 0.75 | DRD3 (0.71) | HRH3KDM4EALDH1A1HPGDDRD3 | |
| SCHEMBL25100761 | 0.74 | KDM4E (0.70) | HRH3KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11080288 | 0.74 | HTR1A (0.51) | HRH3KDM4EHTR1AHTR2A | |
| SCHEMBL2686551 | 0.74 | KDM4E (0.77) | HRH3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2219499 | 0.73 | HRH3 (1.00) | HRH3 | |
| SCHEMBL2625194 | 0.73 | KDM4E (0.75) | HRH3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605739-A | CHYMOTRYPSIN INHIBITORS; PANCREATIC DISORDERS | KOWA CO., LTD. (JP) | 1986-08-12 | — | — | US | claimed |