Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3 | P19429 | 1/20 | 0.56 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.56 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837949 | 0.79 | TNNI3 (0.67) | TNNI3TNNT2TNNC1HKDC1EGFR | |
| SCHEMBL9306981 | 0.78 | CASP6 (0.57) | CNR2ABL1HSD17B10PTGS2 | |
| SCHEMBL9243791 | 0.78 | CNR2 (0.46) | CNR2ABL1CISD1 | |
| SCHEMBL5162119 | 0.77 | TNNI3 (0.47) | TNNI3TNNT2TNNC1HKDC1CNR2 | |
| SCHEMBL11212315 | 0.76 | PRMT1 (0.59) | CNR2ABL1PTGS2ARCISD1 | |
| SCHEMBL10893977 | 0.75 | CASP6 (0.57) | ABL1HSD17B10AR | |
| SCHEMBL11666957 | 0.74 | ENPP2 (0.53) | CNR2EGFRABL1CISD1 | |
| SCHEMBL11666959 | 0.74 | ENPP2 (0.53) | CNR2EGFRABL1CISD1 | |
| SCHEMBL9338716 | 0.74 | PRMT1 (0.59) | CNR2ABL1AR | |
| SCHEMBL9484979 | 0.74 | ABL1 (0.55) | EGFRABL1HSD17B10NAAASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079563-B1 | WATER SOLUBLE 1:2 METAL COMPLEX AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0079563-A2 | Water soluble 1:2 metal complex azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-25 | — | — | EP | disclosed |