Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10878734 | 0.86 | SMN1; SMN2 (0.54) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL10881018 | 0.86 | SMN1; SMN2 (0.58) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL10877460 | 0.81 | SMN1; SMN2 (0.60) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL22192246 | 0.80 | SMN1; SMN2 (0.81) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL8363731 | 0.78 | SMN1; SMN2 (0.69) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL10877465 | 0.77 | ADRB1 (0.57) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL10880581 | 0.77 | ADRB2 (0.64) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL10879903 | 0.77 | SMN1; SMN2 (0.53) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL8390958 | 0.77 | SMN1; SMN2 (0.67) | NR1H4SMN1; SMN2LMNASTAT3MAPT | |
| SCHEMBL8757069 | 0.77 | SMN1; SMN2 (0.67) | NR1H4SMN1; SMN2LMNASTAT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100051-B1 | NEW DERIVATIVES OF 1-ALKYLAMINE-(4(P-ALKYLOXY-BENZAMIDE)PHENOXY)-2-PROPANOL, HAVING BETA-SYMPATHOLYTIC ACTIVITY, THEIR SALTS, AND PRODUCTION PROCESSES THEREOF | A. Menarini S.a.S. (IT) | 1986-04-09 | — | — | EP | claimed |