SCHEMBL10879201

SCHEMBL10879201

COC(=O)c1c(C)c2ccc(N(C)C)cc2oc1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 1/20 0.50
LRP6 O75581 7/20 0.47
SLC16A3 O15427 1/20 0.45
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 5/20 0.45
GLA P06280 2/20 0.45
ATM Q13315 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HTT P42858 2/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 1/20 0.44
KLK7 P49862 1/20 0.44
HPGD P15428 3/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14111513 0.84 ALDH1A1 (0.47) CCR4SLC16A3ALDH1A1KDM4EGLA
SCHEMBL4955063 0.84 CCR4 (0.52) CCR4SLC16A3ALDH1A1KDM4EGLA
SCHEMBL10849966 0.82 HSD17B3 (0.65) CCR4ALDH1A1KDM4EGLAHSD17B10
SCHEMBL17210849 0.81 CA12 (0.50) ALDH1A1KDM4EHSD17B10MAPTGAA
SCHEMBL10881037 0.80 CCR4 (0.62) CCR4SLC16A3ALDH1A1KDM4EGLA
SCHEMBL17941685 0.79 KDM4E (0.66) ALDH1A1KDM4EGLAATMHSD17B10
SCHEMBL21457100 0.77 KMT2A (0.42) CCR4SLC16A3ALDH1A1KDM4EGLA
SCHEMBL21457017 0.77 KMT2A (0.42) CCR4SLC16A3ALDH1A1KDM4EGLA
SCHEMBL13432101 0.76 ALDH1A1 (0.68) SLC16A3ALDH1A1KDM4EGLAATM
SCHEMBL4956069 0.76 CCR4 (0.49) CCR4SLC16A3ALDH1A1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006271-B2 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1986-01-22 EP disclosed
EP-0006271-B1 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1982-03-31 EP disclosed
EP-0006271-A1 Washing and softening compositions containing nonionic brightener THE PROCTER & GAMBLE COMPANY (US) 1980-01-09 EP disclosed