Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655618 | 0.87 | HTT (0.48) | CRHBPCRHR2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6566905 | 0.85 | CA12 (0.62) | CRHBPCRHR2ALDH1A1TDP1MAPT | |
| SCHEMBL231452 | 0.84 | ALDH1A1 (0.47) | CRHBPCRHR2ALDH1A1MAPTHTT | |
| SCHEMBL890895 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TDP1ALOX15MAPT | |
| SCHEMBL28536038 | 0.82 | CA12 (0.62) | CRHBPCRHR2ALDH1A1CYP3A4TDP1 | |
| Ammonia Solution, Strong SCHEMBL18152533 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1ALOX15MAPT | |
| SCHEMBL30894817 | 0.80 | TDP1 (0.59) | ALDH1A1CYP3A4TDP1ALOX15MAPT | |
| SCHEMBL6241415 | 0.80 | TDP1 (0.59) | ALDH1A1CYP3A4TDP1ALOX15MAPT | |
| SCHEMBL13761375 | 0.80 | LMNA (0.60) | ALDH1A1CYP3A4TDP1ALOX15MAPT | |
| SCHEMBL16392517 | 0.79 | CYP19A1 (0.51) | CRHBPCRHR2ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065811-B1 | DISPERSE AZOPYRIMIDINE DYESTUFFS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-02 | — | — | EP | disclosed |
| EP-0065811-A1 | Disperse azopyrimidine dyestuffs | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |