Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 13/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246885 | 0.80 | MAOA (0.41) | GRM2MAOAMAOB | |
| SCHEMBL9425772 | 0.80 | GRM2 (0.42) | CALML3GRM2MAOAMAOBF10 | |
| SCHEMBL9425328 | 0.69 | MAOA (0.41) | CALML3GRM2MAOAMAOB | |
| SCHEMBL9425927 | 0.68 | GRM2 (0.43) | CALML3GRM2MAOAMAOB | |
| SCHEMBL6607536 | 0.67 | MAOA (0.56) | CALML3GRM2MAOAMAOB | |
| SCHEMBL10881242 | 0.67 | MAOA (0.56) | CALML3GRM2MAOAMAOB | |
| SCHEMBL11592601 | 0.65 | GRM2 (0.60) | GRM2 | |
| SCHEMBL10879427 | 0.65 | GRM2 (0.44) | GRM2F10 | |
| SCHEMBL7298956 | 0.64 | GRM2 (0.69) | GRM2F10 | |
| SCHEMBL10879568 | 0.64 | GRM2 (0.43) | GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050827-B1 | 3-(P-ALKYLSULFONYLPHENYL)-AND 3-(P-ALKYLSULFINYLPHENYL)OXAZOLIDINONE DERIVATIVES AS ANTI-BACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |