SCHEMBL11246885

SCHEMBL11246885

Cc1csc(N2CC(CCl)OC2=O)c1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
GRM2 Q14416 13/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9425328 0.86 MAOA (0.41) MAOAMAOBGRM2
SCHEMBL10881242 0.86 MAOA (0.56) MAOAMAOBGRM2
SCHEMBL6607536 0.86 MAOA (0.56) MAOAMAOBGRM2
SCHEMBL9425772 0.80 GRM2 (0.42) MAOAMAOBGRM2
SCHEMBL10879438 0.80 CALML3 (0.32) MAOAMAOBGRM2
SCHEMBL5235135 0.80 GRM2 (0.40) MAOAMAOBGRM2
SCHEMBL5237207 0.77 MAOA (0.53) MAOAMAOB
SCHEMBL5234303 0.77 MAOA (0.38) MAOAMAOBGRM2
SCHEMBL7164287 0.76 GRM2 (0.42) MAOAMAOBGRM2
SCHEMBL7082498 0.75 GRM2 (0.43) MAOAMAOBGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4128654-A BACTERICIDE, FUNGICIDE, PLANT DISEASES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-05 US claimed
EP-0050827-A1 3-(p-Alkylsulfonylphenyl)-and 3-(p-alkylsulfinylphenyl)oxazolidinone derivatives as anti-bacterial agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-05 EP disclosed
US-4128654-A BACTERICIDE, FUNGICIDE, PLANT DISEASES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-05 US disclosed